Many studies on memory and learning utilize the immediate early gene c-Fos as an indicator of recent synaptic activity. By quantifying c-Fos positive neurons, we can compare activity across different populations in the brain, and analyze co-labelled neurons with other useful cell markers such as BrdU and Doublecortin. Our lab…
Continuing on… 1) 31.20/C37 – Dentate network activity modulates integration of newborn granule cells *F. KLEINE BORGMANN1, J. GRÄFF2, N. TONI3, I. M. MANSUY4,5, S. JESSBERGER1; 1Inst. of Cell Biology, Swiss Federal Inst. of Technol. (ETH), Zürich, Switzerland; 2Brain Res. Inst., Univ. of Zürich, Zürich, Switzerland; 3Univ. of Lausanne, Lausanne, Switzerland; 4Brain Res. Inst.,…
Most studies of adult neurogenesis are concerned with neuronal age. Or at least they should be. This is because new neurons develop from a stage where they have no excitatory synapses to one where they have many. If we assume the traditional view that information is stored at excitatory synaptic…