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Retroviral labelling and modulation of new neurons

retrovirus-labelled-dentate-gyrus-neuron

Retroviruses can infect actively dividing neural progenitor cells in the hippocampus and spare non-dividing cells such as mature neurons. With this tool we can selectively label newly born neurons. We can infect neuronal precursor cells at various stages in development and look at a neuron’s morphology at certain ages. This…

Our very own Tim O’Leary won a supply of caffeinated Starbucks beverages at the 2015 UBC Neuroscience Extravaganza, based on his poster presentation skills! Here is a shot of him, droppin’ science. You can also see some more shots of the even here.

Wednesday, Oct 21, 2015, 8:00 AM -12:00 PM, 725.18/BB27. Here is our poster for the 2015 Society for Neuroscience annual meeting. I will be presenting but Tim O’Leary did all the work. Actually, I did a bit of work, but Tim did most of the work. Briefly, this project came about…

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Usually BNS means Behavioral NeuroScience, but once a year it means Beach N Sun for the Psych department’s BNS labs…

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In order to investigate the relationship between an animal’s behaviour and neuronal network activity we are looking at immediate early gene activation in neurons after animals learned a task or were exposed to a novel situation for example. This way we can correlate the activity of certain brain regions with…

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The catFISH (cellular Compartment Analysis of Temporal activity by Fluorescence In Situ Hybridization) method allows us to trace back when a specific neuron has been activated. By using labeling for the RNA of the immediate early gene (IEG) zif268 for example, we know that when we detect its RNA in…

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Is it too late to post photos from our super exciting lab winter holiday ultra-competitive sports event? No?

Introduction: One of main research interests in the Snyder lab is exploring the role of adult-born hippocampal neurons in learning and memory, and whether the function of these neurons changes in non-stressful vs. stressful learning situations. To explore this issue we are using the Morris water maze (MWM), arguably the…

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People are definitely way more excited about neurogenesis in adulthood than in early development. Which is fine. But the emphasis on adult neurogenesis has exposed some gaps in our understanding of the developmental process and so we have embarked on a study to compare neurons born are these different stages…

Systems and Patterns

I wandered up to the lab and found people systematically arranging rat husbandry supplies, as if they knew I was coming, camera in hand.

Category Archives: Uncategorized

Retroviral labelling and modulation of new neurons

Neuroscience Extravaganza Prizewinner, here

SFN 2015: Sex differences in functions of adult neurogenesis

10th Annual BNS = BEACH n’ SUN party

Activity patterns in the hippocampus

catFISH – neuronal activation of single cells at distinct time points

2014 Holiday Bonspiel

Neurogenesis and manipulating stress levels in the water maze

Confocal Images of Dentate Gyrus Development

Systems and Patterns