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Beginning of summer is a good time to get everyone together. Exams are finished. Some have more time to contribute, some move on to new phases of their careers, and new faces arrive. And I now have a compact tripod that fits in my bike bag, which means we can take lab…
The Snyder lab, along with collaborators in the Psychology Department at UBC, will be presenting FIVE posters at SFN this year! Here they are, in order of how hard it was for me to find them on my hard drive, email etc. EARLY SURVIVAL AND DELAYED DEATH OF DEVELOPMENTALLY-BORN DENTATE…
Those who know me know that I love timecourses. Everything changes over time and by characterizing these changes we can understand a phenomenon in its entirety, hopefully. We certainly can’t understand it if we don’t know how it changes over time! Despite all of the neurogenesis timecourse data I’ve summarized previously, there are still some…
This holiday season the Snyder lab gathered for the extremely competitive, second annual, Curling Bonspiel. Here is the action in photos and videos! (videos at the bottom, after the photo gallery)
Retroviruses can infect actively dividing neural progenitor cells in the hippocampus and spare non-dividing cells such as mature neurons. With this tool we can selectively label newly born neurons. We can infect neuronal precursor cells at various stages in development and look at a neuron’s morphology at certain ages. This…
Our very own Tim O’Leary won a supply of caffeinated Starbucks beverages at the 2015 UBC Neuroscience Extravaganza, based on his poster presentation skills! Here is a shot of him, droppin’ science. You can also see some more shots of the even here.
Wednesday, Oct 21, 2015, 8:00 AM -12:00 PM, 725.18/BB27. Here is our poster for the 2015 Society for Neuroscience annual meeting. I will be presenting but Tim O’Leary did all the work. Actually, I did a bit of work, but Tim did most of the work. Briefly, this project came about…
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Usually BNS means Behavioral NeuroScience, but once a year it means Beach N Sun for the Psych department’s BNS labs…
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In order to investigate the relationship between an animal’s behaviour and neuronal network activity we are looking at immediate early gene activation in neurons after animals learned a task or were exposed to a novel situation for example. This way we can correlate the activity of certain brain regions with…
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The catFISH (cellular Compartment Analysis of Temporal activity by Fluorescence In Situ Hybridization) method allows us to trace back when a specific neuron has been activated. By using labeling for the RNA of the immediate early gene (IEG) zif268 for example, we know that when we detect its RNA in…
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Is it too late to post photos from our super exciting lab winter holiday ultra-competitive sports event? No?
Introduction: One of main research interests in the Snyder lab is exploring the role of adult-born hippocampal neurons in learning and memory, and whether the function of these neurons changes in non-stressful vs. stressful learning situations. To explore this issue we are using the Morris water maze (MWM), arguably the…
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People are definitely way more excited about neurogenesis in adulthood than in early development. Which is fine. But the emphasis on adult neurogenesis has exposed some gaps in our understanding of the developmental process and so we have embarked on a study to compare neurons born are these different stages…
I wandered up to the lab and found people systematically arranging rat husbandry supplies, as if they knew I was coming, camera in hand.
Antibodies are funny. Funny in that sometimes they work and sometimes they don’t, sometimes they have different names at different vendors, and sometimes papers do, and sometimes they don’t, specify the catalog number of the antibody they used. So a bit of detective work is required if you want to…
Shaina Cahill¹, Ru Qi Yu¹, Jason Snyder¹ ¹Department of Psychology, University of British Columbia ABSTRACT. The brain is way cooler than all the other organs (combined). I mean, what could possibly be more cool? Maybe if there was a magic drink that could make your brain bigger and stronger? We…
Yesterday we took advantage of some great weather and ate lunch outside while reading the recent neurogenesis-forgetting paper from the Frankland/Josselyn group. It basically flips the field on its head by looking at retrograde effects of neurogenesis on memory, instead of the usual approach of looking at neurogenesis effects on…
One of the leading hypothesized functions for adult hippocampal neurogenesis in memory is pattern separation. Loosely defined, pattern separation is the process of making similar patterns of neural activity more distinct. This is clearly relevant for learning and memory since we have many experiences that are similar to each other…
We demo’d an Olympus FV1200 confocal microscope, which I used to acquire these images of a couple interneurons, labelled with GFP. The video was made with Imaris, which offers some cool moviemaking features that you won’t find in your standard confocal software. BEST VIEWED IN HD!!!
About a year ago I went through a phase of rabid excitement regarding my lab’s website. Then I had to do some experiments, write grants, move across the country. And then today I became rabidly excited again. Things in the Snyder lab are at a critical moment. My first 2…