Tag Archives: stress
Neurogenesis and manipulating stress levels in the water maze
Introduction: One of main research interests in the Snyder lab is exploring the role of adult-born hippocampal neurons in learning and memory, and whether the function of these neurons changes in non-stressful vs. stressful learning situations. To explore this issue we are using the Morris water maze (MWM), arguably the…
New data on neurogenesis, pattern separation, context discrimination and stress
One of the leading hypothesized functions for adult hippocampal neurogenesis in memory is pattern separation. Loosely defined, pattern separation is the process of making similar patterns of neural activity more distinct. This is clearly relevant for learning and memory since we have many experiences that are similar to each other…
Neurogenesis and the septotemporal axis at #SFN11
As I’ve alluded, science, and therefore the SFN meeting where much science is unveiled, is a cycle of confusion and clarification. Currently, confusion may be prevailing in the adult hippocampal neurogenesis field since new neurons have been implicated in everything mammals do – spatial and nonspatial memory, anxiety, depression, addiction,…
In press: The neurogenesis-depression hypothesis, confirmed.
The idea that adult neurogenesis protects individuals from depression is perhaps the single greatest motivator driving neurogenesis research. Not surprisingly, “neurogenesis depression” is the most common behavioral keyword that brings people to this blog (followed closely by “pattern separation”). So I’m excited to say that we will soon be publishing what (I…