Tracing Neurons using FIJI (ImageJ)

Neuron 3c

CONFOCAL IMAGING The image files used in this tutorial were taken using a Leica confocal microscope (model SP8). Using fluorescent imaging technique (*) and an extra spatial filter, this confocal can selectively collect light at a specific z-plane, filtering out any out-of-focus illumination. A series of clear 2D images can …

read more

Lab Portrait March in May

portrait-march

This gallery contains 41 photos.

Beginning of summer is a good time to get everyone together. Exams are finished. Some have more time to contribute, some move on to new phases of their careers, and new faces arrive. And I now have a compact tripod that fits in my bike bag, which means we can take lab …

read more

SFN 2016 Abstracts (5 of em!)

2016logovert 150 x 150

The Snyder lab, along with collaborators in the Psychology Department at UBC, will be presenting FIVE posters at SFN this year! Here they are, in order of how hard it was for me to find them on my hard drive, email etc. EARLY SURVIVAL AND DELAYED DEATH OF DEVELOPMENTALLY-BORN DENTATE …

read more

Survival of neurons born in development vs. adulthood

Those who know me know that I love timecourses. Everything changes over time and by characterizing these changes we can understand a phenomenon in its entirety, hopefully. We certainly can’t understand it if we don’t know how it changes over time! Despite all of the neurogenesis timecourse data I’ve summarized previously, there are still some …

read more

2015 Holiday Bonspiel

This holiday season the Snyder lab gathered for the extremely competitive, second annual, Curling Bonspiel. Here is the action in photos and videos! (videos at the bottom, after the photo gallery)

Retroviral labelling and modulation of new neurons

retrovirus-labelled-dentate-gyrus-neuron

Retroviruses can infect actively dividing neural progenitor cells in the hippocampus and spare non-dividing cells such as mature neurons. With this tool we can selectively label newly born neurons. We can infect neuronal precursor cells at various stages in development and look at a neuron’s morphology at certain ages. This …

read more

Activity patterns in the hippocampus

This gallery contains 16 photos.

In order to investigate the relationship between an animal’s behaviour and neuronal network activity we are looking at immediate early gene activation in neurons after animals learned a task or were exposed to a novel situation for example. This way we can correlate the activity of certain brain regions with …

read more